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Binding of smoothelin-like 1 to tropomyosin and calmodulin is mutually exclusive and regulated by phosphorylation

BACKGROUND: The smoothelin-like 1 protein (SMTNL1) can associate with tropomyosin (Tpm) and calmodulin (CaM), two proteins essential to the smooth muscle contractile process. SMTNL1 is phosphorylated at Ser301 by protein kinase A during calcium desensitization in smooth muscle, yet the effect of SMT...

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Detalles Bibliográficos
Autores principales: Ulke-Lemée, Annegret, Sun, David Hao, Ishida, Hiroaki, Vogel, Hans J., MacDonald, Justin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359911/
https://www.ncbi.nlm.nih.gov/pubmed/28320308
http://dx.doi.org/10.1186/s12858-017-0080-6

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