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Exploring the nature of prediagnostic blood transcriptome markers of chronic lymphocytic leukemia by assessing their overlap with the transcriptome at the clinical stage
BACKGROUND: We recently identified 700 genes whose expression levels were predictive of chronic lymphocytic leukemia (CLL) in a genome-wide gene expression analysis of prediagnostic blood from future cases and matched controls. We hypothesized that a large fraction of these markers were likely relat...
Autores principales: | Vlaanderen, Jelle, Leenders, Max, Chadeau-Hyam, Marc, Portengen, Lützen, Kyrtopoulos, Soterios A., Bergdahl, Ingvar A., Johansson, Ann-Sofie, Hebels, Dennie D.G.A.J., de Kok, Theo M.C.M., Vineis, Paolo, Vermeulen, Roel C.H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360061/ https://www.ncbi.nlm.nih.gov/pubmed/28320322 http://dx.doi.org/10.1186/s12864-017-3627-4 |
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