Decreased cortical FADD protein is associated with clinical dementia and cognitive decline in an elderly community sample

BACKGROUND: FADD (Fas-associated death domain) adaptor is a crucial protein involved in the induction of cell death but also mediates non-apoptotic actions via a phosphorylated form (p-Ser194-FADD). This study investigated the possible association of FADD forms with age-related neuropathologies, cog...

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Detalles Bibliográficos
Autores principales: Ramos-Miguel, Alfredo, García-Sevilla, Jesús A., Barr, Alasdair M., Bayer, Thomas A., Falkai, Peter, Leurgans, Sue E., Schneider, Julie A., Bennett, David A., Honer, William G., García-Fuster, M. Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360099/
https://www.ncbi.nlm.nih.gov/pubmed/28320441
http://dx.doi.org/10.1186/s13024-017-0168-x

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