Cargando…

Lactate dehydrogenase in Toxoplasma gondii controls virulence, bradyzoite differentiation, and chronic infection

In the asexual stages, Toxoplasma gondii stage converts between acute phase rapidly replicating tachyzoites and chronic phase slowly dividing bradyzoites. Correspondingly, T. gondii differentially expresses two distinct genes and isoforms of the lactate dehydrogenase enzyme, expressing LDH1 exclusiv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abdelbaset, Abdelbaset E., Fox, Barbara A., Karram, Mohamed H., Abd Ellah, Mahmoud R., Bzik, David J., Igarashi, Makoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360243/ https://www.ncbi.nlm.nih.gov/pubmed/28323833 http://dx.doi.org/10.1371/journal.pone.0173745

Ejemplares similares

The Toxoplasma gondii Cyst Wall Protein CST1 Is Critical for Cyst Wall Integrity and Promotes Bradyzoite Persistence
por: Tomita, Tadakimi, et al.
Publicado: (2013)

The determinants regulating Toxoplasma gondii bradyzoite development
por: Pan, Ming, et al.
Publicado: (2022)

Identification of compounds that suppress Toxoplasma gondii tachyzoites and bradyzoites
por: Murata, Yuho, et al.
Publicado: (2017)

Acquisition of Host Cytosolic Protein by Toxoplasma gondii Bradyzoites
por: Kannan, Geetha, et al.
Publicado: (2021)

Restriction Checkpoint Controls Bradyzoite Development in Toxoplasma gondii
por: Naumov, Anatoli V., et al.
Publicado: (2022)

Nanosilver Colloid Inhibits Toxoplasma gondii Tachyzoites and Bradyzoites in Vitro
por: SHOJAEE, Saeedeh, et al.
Publicado: (2019)

The transcription of bradyzoite genes in Toxoplasma gondii is controlled by autonomous promoter elements
por: Behnke, Michael S, et al.
Publicado: (2008)

In Vitro Characterization of Protein Effector Export in the Bradyzoite Stage of Toxoplasma gondii
por: Mayoral, Joshua, et al.
Publicado: (2020)

In vitro maturation of Toxoplasma gondii bradyzoites in human myotubes and their metabolomic characterization
por: Christiansen, Céline, et al.
Publicado: (2022)

Analysis of Structures and Epitopes of Surface Antigen Glycoproteins Expressed in Bradyzoites of Toxoplasma gondii
por: Cong, Hua, et al.
Publicado: (2013)

Toxoplasma gondii bradyzoites and tachyzoites isolation from vitreous of atypical necrotizing retinitis
por: Kharel(Sitaula), Ranju, et al.
Publicado: (2018)

Starvation of low-density lipoprotein-derived cholesterol induces bradyzoite conversion in Toxoplasma gondii
por: Ihara, Fumiaki, et al.
Publicado: (2014)

Role of Toxoplasma gondii Chloroquine Resistance Transporter in Bradyzoite Viability and Digestive Vacuole Maintenance
por: Kannan, Geetha, et al.
Publicado: (2019)

MAG2, a Toxoplasma gondii Bradyzoite Stage-Specific Cyst Matrix Protein
por: Tu, Vincent, et al.
Publicado: (2020)

Proximity biotinylation reveals novel secreted dense granule proteins of Toxoplasma gondii bradyzoites
por: Nadipuram, Santhosh Mukund, et al.
Publicado: (2020)

A rapid and simple single‐step method for the purification of Toxoplasma gondii tachyzoites and bradyzoites
por: El‐Ashram, Saeed, et al.
Publicado: (2020)

A transcriptional network required for bradyzoite development in Toxoplasma gondii is dispensable for recrudescent disease
por: Sokol-Borrelli, Sarah L., et al.
Publicado: (2023)

Quantitative Risk Assessment of Oocyst Versus Bradyzoite Foodborne Transmission of Toxoplasma gondii in Brazil
por: Zhu, Sophie, et al.
Publicado: (2023)

Non-replicating Toxoplasma gondii reverses tumor-associated immunosuppression
por: Fox, Barbara A, et al.
Publicado: (2013)

The protein phosphatase 2A holoenzyme is a key regulator of starch metabolism and bradyzoite differentiation in Toxoplasma gondii
por: Wang, Jin-Lei, et al.
Publicado: (2022)

Toxoplasma gondii AP2IX-4 Regulates Gene Expression during Bradyzoite Development
por: Huang, Sherri, et al.
Publicado: (2017)

Invasion of Toxoplasma gondii bradyzoites: Molecular dissection of the moving junction proteins and effective vaccination targets
por: Najm, Rania, et al.
Publicado: (2023)

Toxoplasma gondii seropositivity and the associated risk factors in sheep and pregnant women in El-Minya Governorate, Egypt
por: Abdelbaset, Abdelbaset E., et al.
Publicado: (2020)

Novel Approaches Reveal that Toxoplasma gondii Bradyzoites within Tissue Cysts Are Dynamic and Replicating Entities In Vivo
por: Watts, Elizabeth, et al.
Publicado: (2015)

Rapid inactivation of Toxoplasma gondii bradyzoites during formulation of dry cured ready-to-eat pork sausage
por: Hill, D.E., et al.
Publicado: (2018)

Yeast Three-Hybrid Screen Identifies TgBRADIN/GRA24 as a Negative Regulator of Toxoplasma gondii Bradyzoite Differentiation
por: Odell, Anahi V., et al.
Publicado: (2015)

Succinylated Wheat Germ Agglutinin Colocalizes with the Toxoplasma gondii Cyst Wall Glycoprotein CST1
por: Guevara, Rebekah B., et al.
Publicado: (2020)

The structure of bradyzoite-specific enolase from Toxoplasma gondii reveals insights into its dual cytoplasmic and nuclear functions
por: Ruan, Jiapeng, et al.
Publicado: (2015)

TgLaforin, a glucan phosphatase, reveals the dynamic role of storage polysaccharides in Toxoplasma gondii tachyzoites and bradyzoites
por: Murphy, Robert D., et al.
Publicado: (2023)

Toxoplasma gondii Parasitophorous Vacuole Membrane-Associated Dense Granule Proteins Regulate Maturation of the Cyst Wall
por: Guevara, Rebekah B., et al.
Publicado: (2020)

A Family of Toxoplasma gondii Genes Related to GRA12 Regulate Cyst Burdens and Cyst Reactivation
por: Guevara, Rebekah B., et al.
Publicado: (2021)

The Toxoplasma gondii Rhoptry Kinome Is Essential for Chronic Infection
por: Fox, Barbara A., et al.
Publicado: (2016)

Cancer therapy in a microbial bottle: Uncorking the novel biology of the protozoan Toxoplasma gondii
por: Fox, Barbara A., et al.
Publicado: (2017)

ANK1 and DnaK-TPR, Two Tetratricopeptide Repeat-Containing Proteins Primarily Expressed in Toxoplasma Bradyzoites, Do Not Contribute to Bradyzoite Differentiation
por: Yang, Jichao, et al.
Publicado: (2017)

Toxoplasma gondii Cyclic AMP-Dependent Protein Kinase Subunit 3 Is Involved in the Switch from Tachyzoite to Bradyzoite Development
por: Sugi, Tatsuki, et al.
Publicado: (2016)

Single Cell Transcriptomes of In Vitro Bradyzoite Infected Cells Reveals Toxoplasma gondii Stage Dependent Host Cell Alterations
por: Sugi, Tatsuki, et al.
Publicado: (2022)

A High-Throughput Amenable Dual Luciferase System for Measuring Toxoplasma gondii Bradyzoite Viability after Drug Treatment
por: Smith, David, et al.
Publicado: (2022)

Phenotypes Associated with Knockouts of Eight Dense Granule Gene Loci (GRA2-9) in Virulent Toxoplasma gondii
por: Rommereim, Leah M., et al.
Publicado: (2016)

Nuclear Glycolytic Enzyme Enolase of Toxoplasma gondii Functions as a Transcriptional Regulator
por: Mouveaux, Thomas, et al.
Publicado: (2014)

Toxoplasma gondii Intravacuolar-Network-Associated Dense Granule Proteins Regulate Maturation of the Cyst Matrix and Cyst Wall
por: Guevara, Rebekah B., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_a7u9t5t45aunidbbsumbbol73o