Lawsonia intracellularis exploits β-catenin/Wnt and Notch signalling pathways during infection of intestinal crypt to alter cell homeostasis and promote cell proliferation

Lawsonia intracellularis is an obligate intracellular bacterial pathogen that causes proliferative enteropathy (PE) in pigs. L. intracellularis infection causes extensive intestinal crypt cell proliferation and inhibits secretory and absorptive cell differentiation. However, the affected host upstre...

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Detalles Bibliográficos
Autores principales: Huan, Yang W., Bengtsson, Rebecca J., MacIntyre, Neil, Guthrie, Jack, Finlayson, Heather, Smith, Sionagh H., Archibald, Alan L., Ait-Ali, Tahar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360247/
https://www.ncbi.nlm.nih.gov/pubmed/28323899
http://dx.doi.org/10.1371/journal.pone.0173782

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