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AFM/TIRF force clamp measurements of neurosecretory vesicle tethers reveal characteristic unfolding steps

Although several proteins have been implicated in secretory vesicle tethering, the identity and mechanical properties of the components forming the physical vesicle-plasma membrane link remain unknown. Here we present the first experimental measurements of nanomechanical properties of secretory vesi...

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Detalles Bibliográficos
Autores principales: Harris, Mark C., Cislo, Dillon, Lenz, Joan S., Umbach, Christopher, Lindau, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360256/
https://www.ncbi.nlm.nih.gov/pubmed/28323853
http://dx.doi.org/10.1371/journal.pone.0173993

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