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PIM1-minicircle as a therapeutic treatment for myocardial infarction
PIM1, a pro-survival gene encoding a serine/ threonine kinase, influences cell proliferation and survival. Modification of cardiac progenitor cells (CPCs) or cardiomyocytes with PIM1 using a lentivirus-based delivery method showed long-term improved cardiac function after myocardial infarction (MI)....
Autores principales: | Liu, Nan, Wang, Bingyan J., Broughton, Kathleen M., Alvarez, Roberto, Siddiqi, Sailay, Loaiza, Rebeca, Nguyen, Nicky, Quijada, Pearl, Gude, Natalie, Sussman, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360264/ https://www.ncbi.nlm.nih.gov/pubmed/28323876 http://dx.doi.org/10.1371/journal.pone.0173963 |
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