Myocardial ischemia-reperfusion enhances transcriptional expression of endothelin-1 and vasoconstrictor ET(B) receptors via the protein kinase MEK-ERK1/2 signaling pathway in rat

BACKGROUND: Coronary artery remodelling and vasospasm is a complication of acute myocardial ischemia and reperfusion. The underlying mechanisms are complex, but the vasoconstrictor peptide endothelin-1 is suggested to have an important role. This study aimed to determine whether the expression of en...

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Detalles Bibliográficos
Autores principales: Skovsted, Gry Freja, Kruse, Lars Schack, Berchtold, Lukas Adrian, Grell, Anne-Sofie, Warfvinge, Karin, Edvinsson, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360328/
https://www.ncbi.nlm.nih.gov/pubmed/28323857
http://dx.doi.org/10.1371/journal.pone.0174119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360328/
https://www.ncbi.nlm.nih.gov/pubmed/28323857
http://dx.doi.org/10.1371/journal.pone.0174119

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