Cargando…

Overexpression of c-Jun contributes to sorafenib resistance in human hepatoma cell lines

BACKGROUND: Despite recent advances in treatment strategies, it is still difficult to cure patients with hepatocellular carcinoma (HCC). Sorafenib is the only approved multiple kinase inhibitor for systemic chemotherapy in patients with advanced HCC. The majority of advanced HCC patients are resista...

Descripción completa

Detalles Bibliográficos
Autores principales:	Haga, Yuki, Kanda, Tatsuo, Nakamura, Masato, Nakamoto, Shingo, Sasaki, Reina, Takahashi, Koji, Wu, Shuang, Yokosuka, Osamu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360329/ https://www.ncbi.nlm.nih.gov/pubmed/28323861 http://dx.doi.org/10.1371/journal.pone.0174153

Ejemplares similares

Androgen Receptor Could Be a Potential Therapeutic Target in Patients with Advanced Hepatocellular Carcinoma
por: Kanda, Tatsuo, et al.
Publicado: (2017)

Serum Wisteria Floribunda Agglutinin-Positive Mac-2 Binding Protein Could Not Always Predict Early Cirrhosis in Non-Viral Liver Diseases
por: Haga, Yuki, et al.
Publicado: (2016)

Direct-acting Antivirals and Host-targeting Agents against the Hepatitis A Virus
por: Kanda, Tatsuo, et al.
Publicado: (2015)

MicroRNA-122 Inhibits the Production of Inflammatory Cytokines by Targeting the PKR Activator PACT in Human Hepatic Stellate Cells
por: Nakamura, Masato, et al.
Publicado: (2015)

Possible Involvement of Hepatitis B Virus Infection of Hepatocytes in the Attenuation of Apoptosis in Hepatic Stellate Cells
por: Sasaki, Reina, et al.
Publicado: (2016)

HBV Core Protein Enhances Cytokine Production
por: Kanda, Tatsuo, et al.
Publicado: (2015)

Drug-Induced Liver Injury Associated with Complementary and Alternative Medicines
por: Takahashi, Koji, et al.
Publicado: (2016)

Knockdown of glucose-regulated protein 78 enhances poly(ADP-ribose) polymerase cleavage in human pancreatic cancer cells exposed to endoplasmic reticulum stress
por: JIANG, XIA, et al.
Publicado: (2014)

Cooperative effects of hepatitis B virus and TNF may play important roles in the activation of metabolic pathways through the activation of NF-κB
por: Wu, Shuang, et al.
Publicado: (2016)

Serum microRNA-122 and Wisteria floribunda agglutinin-positive Mac-2 binding protein are useful tools for liquid biopsy of the patients with hepatitis B virus and advanced liver fibrosis
por: Nakamura, Masato, et al.
Publicado: (2017)

Hepatitis C Virus Nonstructural Protein 5A Inhibits MG132-Induced Apoptosis of Hepatocytes in Line with NF-κB-Nuclear Translocation
por: Jiang, Xia, et al.
Publicado: (2015)

Recent Trend of Hepatitis E Virus Infection in Chiba Area, Japan: 3 of 5 Cases with Rheumatoid Arthritis
por: Kanda, Tatsuo, et al.
Publicado: (2015)

Glucose-regulated protein 78 is an antiviral against hepatitis A virus replication
por: Jiang, Xia, et al.
Publicado: (2017)

Successful sofosbuvir treatment with ribavirin dose reduction for chronic hepatitis C virus genotype 2 infection in a patient with ulcerative colitis: a case report
por: Ohta, Yuki, et al.
Publicado: (2016)

Daclatasvir plus Asunaprevir Treatment for Real-World HCV Genotype 1-Infected Patients in Japan
por: Kanda, Tatsuo, et al.
Publicado: (2016)

Effect of Hepatitis C Virus Genotype 1b Core and NS5A Mutations on Response to Peginterferon Plus Ribavirin Combination Therapy
por: Nakamoto, Shingo, et al.
Publicado: (2015)

Treatment of Real-World HCV Genotype 2-Infected Japanese Patients with Sofosbuvir plus Ribavirin
por: Kanda, Tatsuo, et al.
Publicado: (2017)

Sustained Virological Response after 8-Week Treatment of Simeprevir with Peginterferon α-2a plus Ribavirin in a Japanese Female with Hepatitis C Virus Genotype 1b and IL28B Minor Genotype
por: Kanda, Tatsuo, et al.
Publicado: (2015)

Alanine Aminotransferase Elevation during Peginterferon Alpha-2a or Alpha-2b plus Ribavirin Treatment
por: Nakamura, Masato, et al.
Publicado: (2013)

Successful Eradication of Hepatitis C Virus by Interferon-Free Regimens in Two Patients with Advanced Liver Fibrosis following Kidney Transplantation
por: Sasaki, Reina, et al.
Publicado: (2016)

Successful Management of Graft Reinfection of HCV Genotype 2 in Living Donor Liver Transplantation from a Hepatitis B Core Antibody-Positive Donor with Sofosbuvir and Ribavirin
por: Sasaki, Reina, et al.
Publicado: (2016)

Sustained Virologic Response at 24 Weeks after the End of Treatment Is a Better Predictor for Treatment Outcome in Real-World HCV-Infected Patients Treated by HCV NS3/4A Protease Inhibitors with Peginterferon plus Ribavirin
por: Kanda, Tatsuo, et al.
Publicado: (2016)

IFNL4 ss469415590 Variant Is Associated with Treatment Response in Japanese HCV Genotype 1 Infected Individuals Treated with IFN-Including Regimens
por: Miyamura, Tatsuo, et al.
Publicado: (2014)

No Correlation between PNPLA3 rs738409 Genotype and Fatty Liver and Hepatic Cirrhosis in Japanese Patients with HCV
por: Nakamura, Masato, et al.
Publicado: (2013)

Direct-acting Antiviral Agents for the Treatment of Chronic Hepatitis C Virus Infection
por: Kanda, Tatsuo, et al.
Publicado: (2014)

Successful Management of Acute Liver Failure Patients Waiting for Liver Transplantation by On-Line Hemodiafiltration with an Arteriovenous Fistula
por: Haga, Yuki, et al.
Publicado: (2016)

New treatments for genotype 1 chronic hepatitis C – focus on simeprevir
por: Kanda, Tatsuo, et al.
Publicado: (2014)

Superinfection of hepatitis A virus in hepatocytes infected with hepatitis B virus
por: Win, Nan Nwe, et al.
Publicado: (2019)

Real-World Experiences with the Combination Treatment of Ledipasvir plus Sofosbuvir for 12 Weeks in HCV Genotype 1-Infected Japanese Patients: Achievement of a Sustained Virological Response in Previous Users of Peginterferon plus Ribavirin with HCV NS3/4A Inhibitors
por: Kanda, Tatsuo, et al.
Publicado: (2017)

Successful retreatment with sofosbuvir plus ledipasvir for cirrhotic patients with hepatitis C virus genotype 1b, who discontinued the prior treatment with asunaprevir plus daclatasvir: A case series and review of the literature
por: Haga, Yuki, et al.
Publicado: (2017)

Acute Liver Injury in a Patient with Alcohol Dependence: A Case Resembling Autoimmune Hepatitis or Drug-Induced Liver Injury
por: Hayashi, Masahiro, et al.
Publicado: (2014)

Occurrence and Recurrence of Hepatocellular Carcinoma Were Not Rare Events during Phlebotomy in Older Hepatitis C Virus-Infected Patients
por: Kanda, Tatsuo, et al.
Publicado: (2014)

Acute Liver Failure Associated with Propylthiouracil in a Pregnant 26-Year-Old Woman
por: Miyamura, Tatsuo, et al.
Publicado: (2013)

Ultra-Deep Sequencing Analysis of the Hepatitis A Virus 5'-Untranslated Region among Cases of the Same Outbreak from a Single Source
por: Wu, Shuang, et al.
Publicado: (2013)

Hepatic STAT1-Nuclear Translocation and Interleukin 28B Polymorphisms Predict Treatment Outcomes in Hepatitis C Virus Genotype 1-Infected Patients
por: Miyamura, Tatsuo, et al.
Publicado: (2011)

Hepatitis C Virus Nonstructural Protein 5A Inhibits Thapsigargin-Induced Apoptosis
por: Jiang, Xia, et al.
Publicado: (2014)

Hepatitis A Virus Infection and Molecular Research
por: Kanda, Tatsuo, et al.
Publicado: (2022)

Successful retreatment with grazoprevir and elbasvir for patients infected with hepatitis C virus genotype 1b, who discontinued prior treatment with NS5A inhibitor-including regimens due to adverse events
por: Kanda, Tatsuo, et al.
Publicado: (2018)

Discrepancy between Hepatitis C Virus Genotypes and NS4-Based Serotypes: Association with Their Subgenomic Sequences
por: Win, Nan Nwe, et al.
Publicado: (2017)

Roles of ITPA and IL28B Genotypes in Chronic Hepatitis C Patients Treated with Peginterferon Plus Ribavirin
por: Miyamura, Tatsuo, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_dkfl3a7ptrac2u8ojqti1ts3to