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Notoginsenoside R1 attenuates glucose-induced podocyte injury via the inhibition of apoptosis and the activation of autophagy through the PI3K/Akt/mTOR signaling pathway
Injury to terminally differentiated podocytes contributes ignificantly to proteinuria and glomerulosclerosis. The aim of this study was to examine the protective effects of notoginsenoside R1 (NR1) on the maintenance of podocyte number and foot process architecture via the inhibition of apoptosis, t...
Autores principales: | Huang, Guodong, Zou, Bingyu, Lv, Jianzhen, Li, Tongyu, Huai, Guoli, Xiang, Shaowei, Lu, Shilong, Luo, Huan, Zhang, Yaping, Jin, Yi, Wang, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360354/ https://www.ncbi.nlm.nih.gov/pubmed/28112381 http://dx.doi.org/10.3892/ijmm.2017.2864 |
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