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Renin-angiotensin system activation accelerates atherosclerosis in experimental renal failure by promoting endoplasmic reticulum stress-related inflammation

In this study, we investigated the association between the renin-angiotensin system (RAS), endoplasmic reticulum (ER) stress and atherosclerosis (AS) in uremic apolipo-protein E knockout (apoE(−/−)) mice. Mild uremia was induced by a 5/6 nephrectomy (5/6 Nx) in 10-week-old apoE(−/−) mice. Four weeks...

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Detalles Bibliográficos
Autores principales:	Yang, Jia, Zhang, Xi, Yu, Xinyi, Tang, Weixue, Gan, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360357/ https://www.ncbi.nlm.nih.gov/pubmed/28098884 http://dx.doi.org/10.3892/ijmm.2017.2856

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