Cargando…

Hypoxia enhances the wound-healing potential of adipose-derived stem cells in a novel human primary keratinocyte-based scratch assay

Preclinical studies have suggested that paracrine factors from adipose-derived stem cells (ASCs) promote the healing of chronic wounds, and that the exposure of ASCs to hypoxia enhances their wound healing effect. To aid the translation of these findings into clinical use, robust wound models are ne...

Descripción completa

Detalles Bibliográficos
Autores principales:	Riis, Simone, Newman, Rhonda, Ipek, Hilal, Andersen, Jens I., Kuninger, David, Boucher, Shayne, Vemuri, Mohan C., Pennisi, Cristian P., Zachar, Vladimir, Fink, Trine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360363/ https://www.ncbi.nlm.nih.gov/pubmed/28204820 http://dx.doi.org/10.3892/ijmm.2017.2886

Ejemplares similares

Implications of Extracellular Matrix Production by Adipose Tissue-Derived Stem Cells for Development of Wound Healing Therapies
por: Hyldig, Kathrine, et al.
Publicado: (2017)

Mass spectrometry analysis of adipose-derived stem cells reveals a significant effect of hypoxia on pathways regulating extracellular matrix
por: Riis, Simone, et al.
Publicado: (2016)

Moderate Hypoxia Influences Potassium Outward Currents in Adipose-Derived Stem Cells
por: Prasad, Mayuri, et al.
Publicado: (2014)

Distinct Dominant Lineage from In Vitro Expanded Adipose-Derived Stem Cells (ASCs) Exhibits Enhanced Wound Healing Properties
por: Peng, Qiuyue, et al.
Publicado: (2022)

Hypoxia Enhances Differentiation of Adipose Tissue-Derived Stem Cells toward the Smooth Muscle Phenotype
por: Wang, Fang, et al.
Publicado: (2018)

Correction: Peng et al. Distinct Dominant Lineage from In Vitro Expanded Adipose-Derived Stem Cells (ASCs) Exhibits Enhanced Wound Healing Properties. Cells 2022, 11, 1236
por: Peng, Qiuyue, et al.
Publicado: (2023)

Discrete adipose-derived stem cell subpopulations may display differential functionality after in vitro expansion despite convergence to a common phenotype distribution
por: Nielsen, Frederik Mølgaard, et al.
Publicado: (2016)

Potency assays for human adipose-derived stem cells as a medicinal product toward wound healing
por: Ren, Guoqiang, et al.
Publicado: (2022)

Multiplex Analysis of Adipose-Derived Stem Cell (ASC) Immunophenotype Adaption to In Vitro Expansion
por: Peng, Qiuyue, et al.
Publicado: (2021)

Correction: Defined Essential 8™ Medium and Vitronectin Efficiently Support Scalable Xeno-Free Expansion of Human Induced Pluripotent Stem Cells in Stirred Microcarrier Culture Systems
por: Badenes, Sara M., et al.
Publicado: (2016)

Defined Essential 8™ Medium and Vitronectin Efficiently Support Scalable Xeno-Free Expansion of Human Induced Pluripotent Stem Cells in Stirred Microcarrier Culture Systems
por: Badenes, Sara M., et al.
Publicado: (2016)

Effect of a DACC-coated dressing on keratinocytes and fibroblasts in wound healing using an in vitro scratch model
por: Morgner, Bianka, et al.
Publicado: (2022)

A Comparative Analysis of the Wound Healing-Related Heterogeneity of Adipose-Derived Stem Cells Donors
por: Ren, Guoqiang, et al.
Publicado: (2022)

Systematic Review of Stem-Cell-Based Therapy of Burn Wounds: Lessons Learned from Animal and Clinical Studies
por: Henriksen, Josefine Lin, et al.
Publicado: (2020)

Self-healing polymers for surface scratch regeneration
por: Ahmed, Sana, et al.
Publicado: (2023)

Development of fully defined xeno-free culture system for the preparation and propagation of cell therapy-compliant human adipose stem cells
por: Patrikoski, Mimmi, et al.
Publicado: (2013)

The role of PRP and adipose tissue-derived keratinocytes on burn wound healing in diabetic rats
por: Hosseini Mansoub, Navid, et al.
Publicado: (2018)

Scratch-Healing Behavior of Ice by Local Sublimation and Condensation
por: Demmenie, Menno, et al.
Publicado: (2022)

Scratch-induced partial skin wounds re-epithelialize by sheets of independently migrating keratinocytes
por: Bornes, Laura, et al.
Publicado: (2020)

Lanthanoids Goes Healing: Lanthanoidic Metallopolymers and Their Scratch Closure Behavior
por: Götz, Stefan, et al.
Publicado: (2020)

Lactobacillus rhamnosus GG Lysate Increases Re-Epithelialization of Keratinocyte Scratch Assays by Promoting Migration
por: Mohammedsaeed, Walaa, et al.
Publicado: (2015)

Sources, Selection, and Microenvironmental Preconditioning of Cells for Urethral Tissue Engineering
por: Xuan, Zongzhe, et al.
Publicado: (2022)

Activation of Protease-Activated Receptor 2 Induces VEGF Independently of HIF-1
por: Rasmussen, Jeppe Grøndahl, et al.
Publicado: (2012)

Shape-Memory Assisted Scratch-Healing of Transparent Thiol-Ene Coatings
por: Lazauskas, Algirdas, et al.
Publicado: (2019)

Naringenin potentiated β-sitosterol healing effect on the scratch wound assay
por: Abbas, Manal Mohammad, et al.
Publicado: (2019)

The EGFR-ERK/JNK-CCL20 Pathway in Scratched Keratinocytes May Underpin Koebnerization in Psoriasis Patients
por: Furue, Kazuhisa, et al.
Publicado: (2020)

Maintaining RNA Integrity for Transcriptomic Profiling of Ex Vivo Cultured Limbal Epithelial Stem Cells after Fluorescence-Activated Cell Sorting (FACS)
por: Liu, Lei, et al.
Publicado: (2017)

Foxn1 expression in keratinocytes is stimulated by hypoxia: further evidence of its role in skin wound healing
por: Kur-Piotrowska, Anna, et al.
Publicado: (2018)

Scratching Counteracts IL-13 Signaling by Upregulating the Decoy Receptor IL-13Rα2 in Keratinocytes
por: Ulzii, Dugarmaa, et al.
Publicado: (2019)

Royal jelly-derived proteins enhance proliferation and migration of human epidermal keratinocytes in an in vitro scratch wound model
por: Lin, Yan, et al.
Publicado: (2019)

Migratory Metrics of Wound Healing: A Quantification Approach for in vitro Scratch Assays
por: Varankar, Sagar S., et al.
Publicado: (2018)

A novel magnet-based scratch method for standardisation of wound-healing assays
por: Fenu, M., et al.
Publicado: (2019)

From Scratch Closure to Electrolyte Barrier Restoration in Self-Healing Polyurethane Coatings
por: Montano, Vincenzo, et al.
Publicado: (2021)

An effective device to enable consistent scratches for in vitro scratch assays
por: Chen, Sixun, et al.
Publicado: (2023)

Instability of standard PCR reference genes in adipose-derived stem cells during propagation, differentiation and hypoxic exposure
por: Fink, Trine, et al.
Publicado: (2008)

Metabolomic Alteration of Oral Keratinocytes and Fibroblasts in Hypoxia
por: Kato, Hiroko, et al.
Publicado: (2021)

Cat scratch disease: What to do with the cat?
por: Okrent Smolar, Avital Lily, et al.
Publicado: (2022)

Scratch Morphology Transformation: An Alternative Method of Scratch Processing on Optical Surface
por: Zhou, Guangqi, et al.
Publicado: (2021)

The Immune Functions of Keratinocytes in Skin Wound Healing
por: Piipponen, Minna, et al.
Publicado: (2020)

Boron-Doped Nanocrystalline Diamond Electrodes for Neural Interfaces: In vivo Biocompatibility Evaluation
por: Alcaide, María, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_geqjcn6t017fp7rqul28j3lcmj