MicroRNA-145 inhibits the activation of the mTOR signaling pathway to suppress the proliferation and invasion of invasive pituitary adenoma cells by targeting AKT3 in vivo and in vitro

PURPOSE: This study was designed to explore how miR-145 regulates the mTOR signaling pathway in invasive pituitary adenoma (IPA) by targeting AKT3. METHODS: A total of 71 cases of IPA tissues and 66 cases of non-IPA tissues were obtained in this study. In vitro, the IPA cells were assigned into blan...

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Detalles Bibliográficos
Autores principales: Zhou, Kai, Fan, Yan-Dong, Wu, Peng-Fei, Duysenbi, Serick, Feng, Zhao-Hai, Du, Guo-Jia, Zhang, Ting-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360400/
https://www.ncbi.nlm.nih.gov/pubmed/28352194
http://dx.doi.org/10.2147/OTT.S118391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360400/
https://www.ncbi.nlm.nih.gov/pubmed/28352194
http://dx.doi.org/10.2147/OTT.S118391

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