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MicroRNA-145 inhibits the activation of the mTOR signaling pathway to suppress the proliferation and invasion of invasive pituitary adenoma cells by targeting AKT3 in vivo and in vitro

PURPOSE: This study was designed to explore how miR-145 regulates the mTOR signaling pathway in invasive pituitary adenoma (IPA) by targeting AKT3. METHODS: A total of 71 cases of IPA tissues and 66 cases of non-IPA tissues were obtained in this study. In vitro, the IPA cells were assigned into blan...

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Detalles Bibliográficos
Autores principales:	Zhou, Kai, Fan, Yan-Dong, Wu, Peng-Fei, Duysenbi, Serick, Feng, Zhao-Hai, Du, Guo-Jia, Zhang, Ting-Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360400/ https://www.ncbi.nlm.nih.gov/pubmed/28352194 http://dx.doi.org/10.2147/OTT.S118391

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