Cargando…

ROCK/actin/MRTF signaling promotes the fibrogenic phenotype of fibroblast-like synoviocytes derived from the temporomandibular joint

Malocclusion caused by abnormal jaw development or muscle overuse during mastication results in abnormal mechanical stress to the tissues surrounding the temporomandibular joint (TMJ). Excessive mechanical stress against soft and hard tissues around the TMJ is involved in the pathogenesis of inflamm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yokota, Seiji, Chosa, Naoyuki, Kyakumoto, Seiko, Kimura, Hitomichi, Ibi, Miho, Kamo, Masaharu, Satoh, Kazuro, Ishisaki, Akira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360431/ https://www.ncbi.nlm.nih.gov/pubmed/28259960 http://dx.doi.org/10.3892/ijmm.2017.2896

Ejemplares similares

Receptor tyrosine kinase ligands and inflammatory cytokines cooperatively suppress the fibrogenic activity in temporomandibular-joint-derived fibroblast-like synoviocytes via mitogen-activated protein kinase kinase/extracellular signal-regulated kinase
por: Matsumoto, Shikino, et al.
Publicado: (2020)

Cell–cell interactions between monocytes/macrophages and synoviocyte-like cells promote inflammatory cell infiltration mediated by augmentation of MCP-1 production in temporomandibular joint
por: Ibi, Miho, et al.
Publicado: (2018)

Extracellular adenosine 5ʹ-diphosphate promotes MCP-1/CCL2 expression via the P2Y(13) purinergic receptor/ERK signaling axis in temporomandibular joint-derived mouse fibroblast-like synoviocytes
por: Yokota, Seiji, et al.
Publicado: (2022)

TGF-β-Operated Growth Inhibition and Translineage Commitment into Smooth Muscle Cells of Periodontal Ligament-Derived Endothelial Progenitor Cells through Smad- and p38 MAPK-Dependent Signals
por: Yoshida, Mariko, et al.
Publicado: (2012)

Zoledronic acid suppresses transforming growth factor-β-induced fibrogenesis by human gingival fibroblasts
por: KOMATSU, YUKO, et al.
Publicado: (2016)

Water-soluble factors eluated from surface pre-reacted glass-ionomer filler promote osteoblastic differentiation of human mesenchymal stem cells
por: Nemoto, Akira, et al.
Publicado: (2018)

IL-1β and TNF-α suppress TGF-β-promoted NGF expression in periodontal ligament-derived fibroblasts through inactivation of TGF-β-induced Smad2/3- and p38 MAPK-mediated signals
por: Ohta, Maiko, et al.
Publicado: (2018)

Transforming growth factor-β1 suppresses bone morphogenetic protein-2-induced mesenchymal-epithelial transition in HSC-4 human oral squamous cell carcinoma cells via Smad1/5/9 pathway suppression
por: Chiba, Takahiro, et al.
Publicado: (2017)

SCRG1 suppresses LPS-induced CCL22 production through ERK1/2 activation in mouse macrophage Raw264.7 cells
por: Inoue, Manabu, et al.
Publicado: (2017)

Two novel mechanisms for maintenance of stemness in mesenchymal stem cells: SCRG1/BST1 axis and cell–cell adhesion through N-cadherin()
por: Chosa, Naoyuki, et al.
Publicado: (2018)

Establishment of immortalized mesenchymal stem cells derived from the submandibular glands of tdTomato transgenic mice
por: FURUKAWA, SHINJI, et al.
Publicado: (2015)

PDGF-induced PI3K-mediated signaling enhances the TGF-β-induced osteogenic differentiation of human mesenchymal stem cells in a TGF-β-activated MEK-dependent manner
por: YOKOTA, JUN, et al.
Publicado: (2014)

Establishment of mesenchymal stem cell lines derived from the bone marrow of green fluorescent protein-transgenic mice exhibiting a diversity in intracellular transforming growth factor-β and bone morphogenetic protein signaling
por: SAWADA, SHUNSUKE, et al.
Publicado: (2016)

TGF-β1 induces N-cadherin expression by upregulating Sox9 expression and promoting its nuclear translocation in human oral squamous cell carcinoma cells
por: Hirano, Taifu, et al.
Publicado: (2020)

Effects of apatite particle size in two apatite/collagen composites on the osteogenic differentiation profile of osteoblastic cells
por: HATAKEYAMA, WATARU, et al.
Publicado: (2013)

VEGF-C and TGF-β reciprocally regulate mesenchymal stem cell commitment to differentiation into lymphatic endothelial or osteoblastic phenotypes
por: IGARASHI, YASUYUKI, et al.
Publicado: (2016)

Enhancement of Anti-Inflammatory and Osteogenic Abilities of Mesenchymal Stem Cells via Cell-to-Cell Adhesion to Periodontal Ligament-Derived Fibroblasts
por: Suzuki, Keita, et al.
Publicado: (2017)

Key Fibrogenic Signaling
por: He, Weichun, et al.
Publicado: (2015)

Gene regulation and deregulation by MAL/MRTF coactivators
por: Posern, G
Publicado: (2009)

MRTF: Basic Biology and Role in Kidney Disease
por: Miranda, Maria Zena, et al.
Publicado: (2021)

Inflammation Writes the Fibrogenic Code
por: Friedersdorf, Matthew, et al.
Publicado: (2021)

Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts
por: Esnault, Cyril, et al.
Publicado: (2014)

Fibroblast growth factor 2 inhibits the expression of stromal cell-derived factor 1α in periodontal ligament cells derived from human permanent teeth in vitro
por: ASAKAWA, TAKEYOSHI, et al.
Publicado: (2011)

TGF-β in developmental and fibrogenic EMTs
por: Lee, Jun Ho, et al.
Publicado: (2022)

Profibrotic epithelial phenotype: a central role for MRTF and TAZ
por: Bialik, Janne Folke, et al.
Publicado: (2019)

MRTF specifies a muscle-like contractile module in Porifera
por: Colgren, J., et al.
Publicado: (2022)

Novel SCRG1/BST1 axis regulates self-renewal, migration, and osteogenic differentiation potential in mesenchymal stem cells
por: Aomatsu, Emiko, et al.
Publicado: (2014)

Cyclosporine A inhibits MRTF‐SRF signaling through Na(+)/K(+) ATPase inhibition and actin remodeling
por: Burat, Bastien, et al.
Publicado: (2019)

FTO modulates fibrogenic responses in obstructive nephropathy
por: Wang, Chao-Yung, et al.
Publicado: (2016)

Inflammatory and Fibrogenic Factors in Proliferative Vitreoretinopathy Development
por: Chaudhary, Rishika, et al.
Publicado: (2020)

Sonic Hedgehog Promotes Proliferation and Migration of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via Rho/ROCK Signaling
por: Hu, Zaiying, et al.
Publicado: (2022)

MRTF/SRF dependent transcriptional regulation of TAZ in breast cancer cells
por: Liu, Chen-Ying, et al.
Publicado: (2016)

Regulation of MRTF-A by JMY via a nucleation-independent mechanism
por: Kluge, Franziska, et al.
Publicado: (2018)

MRTF-A can activate Nrf2 to increase the resistance to doxorubicin
por: Xu, Yao, et al.
Publicado: (2016)

Migration arrest of chemoresistant leukemia cells mediated by MRTF-SRF pathway
por: Morimatsu, Maho, et al.
Publicado: (2020)

Regulation of Dendritic Synaptic Morphology and Transcription by the SRF Cofactor MKL/MRTF
por: Tabuchi, Akiko, et al.
Publicado: (2021)

Epithelial Protein Lost in Neoplasm α (Eplin-α) is transcriptionally regulated by G-actin and MAL/MRTF coactivators
por: Leitner, Laura, et al.
Publicado: (2010)

An actin-regulated importin α/β-dependent extended bipartite NLS directs nuclear import of MRTF-A
por: Pawłowski, Rafał, et al.
Publicado: (2010)

The actin-MRTF-SRF transcriptional circuit controls tubulin acetylation via α-TAT1 gene expression
por: Fernández-Barrera, Jaime, et al.
Publicado: (2018)

Nuclear-capture of endosomes depletes nuclear G-actin to promote SRF/MRTF activation and cancer cell invasion
por: Marco, Sergi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_d3ivcom42pt79h1tibbv8rkfco