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SMOC can act as both an antagonist and an expander of BMP signaling

The matricellular protein SMOC (Secreted Modular Calcium binding protein) is conserved phylogenetically from vertebrates to arthropods. We showed previously that SMOC inhibits bone morphogenetic protein (BMP) signaling downstream of its receptor via activation of mitogen-activated protein kinase (MA...

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Detalles Bibliográficos
Autores principales: Thomas, J Terrig, Eric Dollins, D, Andrykovich, Kristin R, Chu, Tehyen, Stultz, Brian G, Hursh, Deborah A, Moos, Malcolm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360445/
https://www.ncbi.nlm.nih.gov/pubmed/28323621
http://dx.doi.org/10.7554/eLife.17935