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SMOC can act as both an antagonist and an expander of BMP signaling
The matricellular protein SMOC (Secreted Modular Calcium binding protein) is conserved phylogenetically from vertebrates to arthropods. We showed previously that SMOC inhibits bone morphogenetic protein (BMP) signaling downstream of its receptor via activation of mitogen-activated protein kinase (MA...
Autores principales: | Thomas, J Terrig, Eric Dollins, D, Andrykovich, Kristin R, Chu, Tehyen, Stultz, Brian G, Hursh, Deborah A, Moos, Malcolm |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360445/ https://www.ncbi.nlm.nih.gov/pubmed/28323621 http://dx.doi.org/10.7554/eLife.17935 |
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