Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells

PURPOSE: The RPE cell line ARPE-19 provides a dependable and widely used alternative to native RPE. However, replication of the native RPE phenotype becomes more difficult because these cells lose their specialized phenotype after multiple passages. Compounding this problem is the widespread use of...

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Detalles Bibliográficos
Autores principales: Samuel, William, Jaworski, Cynthia, Postnikova, Olga. A., Kutty, R. Krishnan, Duncan, Todd, Tan, Li Xuan, Poliakov, Eugenia, Lakkaraju, Aparna, Redmond, T. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360456/
https://www.ncbi.nlm.nih.gov/pubmed/28356702

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