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Removal of Integrated Hepatitis B Virus DNA Using CRISPR-Cas9

The presence of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) and the permanent integration of HBV DNA into the host genome confers the risk of viral reactivation and hepatocellular carcinoma. Nucleoside/nucleotide analogs alone have little or no capacity to eliminate replicative H...

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Detalles Bibliográficos
Autores principales:	Li, Hao, Sheng, Chunyu, Wang, Shan, Yang, Lang, Liang, Yuan, Huang, Yong, Liu, Hongbo, Li, Peng, Yang, Chaojie, Yang, Xiaoxia, Jia, Leili, Xie, Jing, Wang, Ligui, Hao, Rongzhang, Du, Xinying, Xu, Dongping, Zhou, Jianjun, Li, Mingzhen, Sun, Yansong, Tong, Yigang, Li, Qiao, Qiu, Shaofu, Song, Hongbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360708/ https://www.ncbi.nlm.nih.gov/pubmed/28382278 http://dx.doi.org/10.3389/fcimb.2017.00091

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