Old Mice Accumulate Activated Effector CD4 T Cells Refractory to Regulatory T Cell-Induced Immunosuppression

Chronic low-grade inflammation and reduced lymphocyte potency are implicated in the pathogenesis of major illnesses associated with aging. Whether this immune phenotype results from a loss of cell-mediated regulation or intrinsic dysregulated function of effector T cells (Teffs) requires further res...

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Detalles Bibliográficos
Autores principales: Harpaz, Idan, Bhattacharya, Udayan, Elyahu, Yehezqel, Strominger, Itai, Monsonego, Alon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360761/
https://www.ncbi.nlm.nih.gov/pubmed/28382033
http://dx.doi.org/10.3389/fimmu.2017.00283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360761/
https://www.ncbi.nlm.nih.gov/pubmed/28382033
http://dx.doi.org/10.3389/fimmu.2017.00283

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