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Old Mice Accumulate Activated Effector CD4 T Cells Refractory to Regulatory T Cell-Induced Immunosuppression

Chronic low-grade inflammation and reduced lymphocyte potency are implicated in the pathogenesis of major illnesses associated with aging. Whether this immune phenotype results from a loss of cell-mediated regulation or intrinsic dysregulated function of effector T cells (Teffs) requires further res...

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Detalles Bibliográficos
Autores principales:	Harpaz, Idan, Bhattacharya, Udayan, Elyahu, Yehezqel, Strominger, Itai, Monsonego, Alon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360761/ https://www.ncbi.nlm.nih.gov/pubmed/28382033 http://dx.doi.org/10.3389/fimmu.2017.00283

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