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Functional Roles of microRNAs in Agronomically Important Plants—Potential as Targets for Crop Improvement and Protection
MicroRNAs (miRNAs) are a class of small non-coding RNAs that have recently emerged as important regulators of gene expression, mainly through cleavage and/or translation inhibition of the target mRNAs during or after transcription. miRNAs play important roles by regulating a multitude of biological...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360763/ https://www.ncbi.nlm.nih.gov/pubmed/28382044 http://dx.doi.org/10.3389/fpls.2017.00378 |
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author | Djami-Tchatchou, Arnaud T. Sanan-Mishra, Neeti Ntushelo, Khayalethu Dubery, Ian A. |
author_facet | Djami-Tchatchou, Arnaud T. Sanan-Mishra, Neeti Ntushelo, Khayalethu Dubery, Ian A. |
author_sort | Djami-Tchatchou, Arnaud T. |
collection | PubMed |
description | MicroRNAs (miRNAs) are a class of small non-coding RNAs that have recently emerged as important regulators of gene expression, mainly through cleavage and/or translation inhibition of the target mRNAs during or after transcription. miRNAs play important roles by regulating a multitude of biological processes in plants which include maintenance of genome integrity, development, metabolism, and adaptive responses toward environmental stresses. The increasing population of the world and their food demands requires focused efforts for the improvement of crop plants to ensure sustainable food production. Manipulation of mRNA transcript abundance via miRNA control provides a unique strategy for modulating differential plant gene expression and miRNAs are thus emerging as the next generation targets for genetic engineering for improvement of the agronomic properties of crops. However, a deeper understanding of its potential and the mechanisms involved will facilitate the design of suitable strategies to obtain the desirable traits with minimum trade-offs in the modified crops. In this regard, this review highlights the diverse roles of conserved and newly identified miRNAs in various food and industrial crops and recent advances made in the uses of miRNAs to improve plants of agronomically importance so as to significantly enhance crop yields and increase tolerance to various environmental stress agents of biotic—or abiotic origin. |
format | Online Article Text |
id | pubmed-5360763 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-53607632017-04-05 Functional Roles of microRNAs in Agronomically Important Plants—Potential as Targets for Crop Improvement and Protection Djami-Tchatchou, Arnaud T. Sanan-Mishra, Neeti Ntushelo, Khayalethu Dubery, Ian A. Front Plant Sci Plant Science MicroRNAs (miRNAs) are a class of small non-coding RNAs that have recently emerged as important regulators of gene expression, mainly through cleavage and/or translation inhibition of the target mRNAs during or after transcription. miRNAs play important roles by regulating a multitude of biological processes in plants which include maintenance of genome integrity, development, metabolism, and adaptive responses toward environmental stresses. The increasing population of the world and their food demands requires focused efforts for the improvement of crop plants to ensure sustainable food production. Manipulation of mRNA transcript abundance via miRNA control provides a unique strategy for modulating differential plant gene expression and miRNAs are thus emerging as the next generation targets for genetic engineering for improvement of the agronomic properties of crops. However, a deeper understanding of its potential and the mechanisms involved will facilitate the design of suitable strategies to obtain the desirable traits with minimum trade-offs in the modified crops. In this regard, this review highlights the diverse roles of conserved and newly identified miRNAs in various food and industrial crops and recent advances made in the uses of miRNAs to improve plants of agronomically importance so as to significantly enhance crop yields and increase tolerance to various environmental stress agents of biotic—or abiotic origin. Frontiers Media S.A. 2017-03-22 /pmc/articles/PMC5360763/ /pubmed/28382044 http://dx.doi.org/10.3389/fpls.2017.00378 Text en Copyright © 2017 Djami-Tchatchou, Sanan-Mishra, Ntushelo and Dubery. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Plant Science Djami-Tchatchou, Arnaud T. Sanan-Mishra, Neeti Ntushelo, Khayalethu Dubery, Ian A. Functional Roles of microRNAs in Agronomically Important Plants—Potential as Targets for Crop Improvement and Protection |
title | Functional Roles of microRNAs in Agronomically Important Plants—Potential as Targets for Crop Improvement and Protection |
title_full | Functional Roles of microRNAs in Agronomically Important Plants—Potential as Targets for Crop Improvement and Protection |
title_fullStr | Functional Roles of microRNAs in Agronomically Important Plants—Potential as Targets for Crop Improvement and Protection |
title_full_unstemmed | Functional Roles of microRNAs in Agronomically Important Plants—Potential as Targets for Crop Improvement and Protection |
title_short | Functional Roles of microRNAs in Agronomically Important Plants—Potential as Targets for Crop Improvement and Protection |
title_sort | functional roles of micrornas in agronomically important plants—potential as targets for crop improvement and protection |
topic | Plant Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360763/ https://www.ncbi.nlm.nih.gov/pubmed/28382044 http://dx.doi.org/10.3389/fpls.2017.00378 |
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