A 64-Year-Old Woman with Chest Pain, Limb Weakness, and Endometrial Cancer

Necrotizing autoimmune myopathy (NAM) is a rare subgroup of idiopathic inflammatory myopathies (IIM). This pathology usually affects proximal limb muscles and in some cases the myocardium. Patients usually display proximal limb weakness. Muscular biopsy is required to confirm the diagnosis. We repor...

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Detalles Bibliográficos
Autores principales: Ponthus, Simon, Kherad, Omar, Petriccioli, Nicole, Lobrinus, Johannes Alexander, Guerne, Pierre-André A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360936/
https://www.ncbi.nlm.nih.gov/pubmed/28373922
http://dx.doi.org/10.1155/2017/1891897
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author Ponthus, Simon
Kherad, Omar
Petriccioli, Nicole
Lobrinus, Johannes Alexander
Guerne, Pierre-André A.
author_facet Ponthus, Simon
Kherad, Omar
Petriccioli, Nicole
Lobrinus, Johannes Alexander
Guerne, Pierre-André A.
author_sort Ponthus, Simon
collection PubMed
description Necrotizing autoimmune myopathy (NAM) is a rare subgroup of idiopathic inflammatory myopathies (IIM). This pathology usually affects proximal limb muscles and in some cases the myocardium. Patients usually display proximal limb weakness. Muscular biopsy is required to confirm the diagnosis. We report the case of a 64-year-old woman with an atypical first presentation of NAM, manifested by chest pain in the context of metastatic endometrial cancer. The diagnosis of NAM was however made when she returned a second time with proximal limb weakness. A treatment with prednisone was then initiated, to which rituximab was rapidly associated, beside a specific chemotherapy.
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spelling pubmed-53609362017-04-03 A 64-Year-Old Woman with Chest Pain, Limb Weakness, and Endometrial Cancer Ponthus, Simon Kherad, Omar Petriccioli, Nicole Lobrinus, Johannes Alexander Guerne, Pierre-André A. Case Rep Rheumatol Case Report Necrotizing autoimmune myopathy (NAM) is a rare subgroup of idiopathic inflammatory myopathies (IIM). This pathology usually affects proximal limb muscles and in some cases the myocardium. Patients usually display proximal limb weakness. Muscular biopsy is required to confirm the diagnosis. We report the case of a 64-year-old woman with an atypical first presentation of NAM, manifested by chest pain in the context of metastatic endometrial cancer. The diagnosis of NAM was however made when she returned a second time with proximal limb weakness. A treatment with prednisone was then initiated, to which rituximab was rapidly associated, beside a specific chemotherapy. Hindawi 2017 2017-03-08 /pmc/articles/PMC5360936/ /pubmed/28373922 http://dx.doi.org/10.1155/2017/1891897 Text en Copyright © 2017 Simon Ponthus et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ponthus, Simon
Kherad, Omar
Petriccioli, Nicole
Lobrinus, Johannes Alexander
Guerne, Pierre-André A.
A 64-Year-Old Woman with Chest Pain, Limb Weakness, and Endometrial Cancer
title A 64-Year-Old Woman with Chest Pain, Limb Weakness, and Endometrial Cancer
title_full A 64-Year-Old Woman with Chest Pain, Limb Weakness, and Endometrial Cancer
title_fullStr A 64-Year-Old Woman with Chest Pain, Limb Weakness, and Endometrial Cancer
title_full_unstemmed A 64-Year-Old Woman with Chest Pain, Limb Weakness, and Endometrial Cancer
title_short A 64-Year-Old Woman with Chest Pain, Limb Weakness, and Endometrial Cancer
title_sort 64-year-old woman with chest pain, limb weakness, and endometrial cancer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360936/
https://www.ncbi.nlm.nih.gov/pubmed/28373922
http://dx.doi.org/10.1155/2017/1891897
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