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Monitoring the Changes of Material Properties at Bone-Implant Interface during the Healing Process In Vivo: A Viscoelastic Investigation

The aim of this study was to monitor the changes of viscoelastic properties at bone-implant interface via resonance frequency analysis (RFA) and the Periotest device during the healing process in an experimental rabbit model. Twenty-four dental implants were inserted into the femoral condyles of rab...

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Autores principales: Chen, Hsiang-Ho, Lai, Wei-Yi, Chee, Tze-Jian, Chan, Ya-Hui, Feng, Sheng-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360965/
https://www.ncbi.nlm.nih.gov/pubmed/28373978
http://dx.doi.org/10.1155/2017/1945607
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author Chen, Hsiang-Ho
Lai, Wei-Yi
Chee, Tze-Jian
Chan, Ya-Hui
Feng, Sheng-Wei
author_facet Chen, Hsiang-Ho
Lai, Wei-Yi
Chee, Tze-Jian
Chan, Ya-Hui
Feng, Sheng-Wei
author_sort Chen, Hsiang-Ho
collection PubMed
description The aim of this study was to monitor the changes of viscoelastic properties at bone-implant interface via resonance frequency analysis (RFA) and the Periotest device during the healing process in an experimental rabbit model. Twenty-four dental implants were inserted into the femoral condyles of rabbits. The animals were sacrificed immediately after implant installation or on day 14, 28, or 56 after surgery. Viscoelastic properties at bone-implant interface were evaluated by measuring the implant stability quotient (ISQ) using RFA and by measuring the Periotest values (PTVs) using the Periotest device. The bone/implant specimens were evaluated histopathologically and histomorphometrically to determine the degree of osseointegration (BIC%). The BIC% values at different time points were then compared with the corresponding ISQ values and PTVs. The mean ISQ value increased gradually and reached 81 ± 1.7 on day 56, whereas the mean PTV decreased over time, finally reaching −0.7 ± 0.5 on day 56. Significant correlations were found between ISQ and BIC% (r = 0.701, p < 0.001), PTV and BIC% (r = −0.637, p < 0.05), and ISQ and PTV (r = −0.68, p < 0.05). These results show that there is a positive correlation between implant stability parameters and peri-implant-bone healing, indicating that the RFA and Periotest are useful for measuring changes of viscoelastic properties at bone-implant interface and are reliable for indirectly predicting the degree of osseointegration.
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spelling pubmed-53609652017-04-03 Monitoring the Changes of Material Properties at Bone-Implant Interface during the Healing Process In Vivo: A Viscoelastic Investigation Chen, Hsiang-Ho Lai, Wei-Yi Chee, Tze-Jian Chan, Ya-Hui Feng, Sheng-Wei Biomed Res Int Research Article The aim of this study was to monitor the changes of viscoelastic properties at bone-implant interface via resonance frequency analysis (RFA) and the Periotest device during the healing process in an experimental rabbit model. Twenty-four dental implants were inserted into the femoral condyles of rabbits. The animals were sacrificed immediately after implant installation or on day 14, 28, or 56 after surgery. Viscoelastic properties at bone-implant interface were evaluated by measuring the implant stability quotient (ISQ) using RFA and by measuring the Periotest values (PTVs) using the Periotest device. The bone/implant specimens were evaluated histopathologically and histomorphometrically to determine the degree of osseointegration (BIC%). The BIC% values at different time points were then compared with the corresponding ISQ values and PTVs. The mean ISQ value increased gradually and reached 81 ± 1.7 on day 56, whereas the mean PTV decreased over time, finally reaching −0.7 ± 0.5 on day 56. Significant correlations were found between ISQ and BIC% (r = 0.701, p < 0.001), PTV and BIC% (r = −0.637, p < 0.05), and ISQ and PTV (r = −0.68, p < 0.05). These results show that there is a positive correlation between implant stability parameters and peri-implant-bone healing, indicating that the RFA and Periotest are useful for measuring changes of viscoelastic properties at bone-implant interface and are reliable for indirectly predicting the degree of osseointegration. Hindawi 2017 2017-03-08 /pmc/articles/PMC5360965/ /pubmed/28373978 http://dx.doi.org/10.1155/2017/1945607 Text en Copyright © 2017 Hsiang-Ho Chen et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Chen, Hsiang-Ho
Lai, Wei-Yi
Chee, Tze-Jian
Chan, Ya-Hui
Feng, Sheng-Wei
Monitoring the Changes of Material Properties at Bone-Implant Interface during the Healing Process In Vivo: A Viscoelastic Investigation
title Monitoring the Changes of Material Properties at Bone-Implant Interface during the Healing Process In Vivo: A Viscoelastic Investigation
title_full Monitoring the Changes of Material Properties at Bone-Implant Interface during the Healing Process In Vivo: A Viscoelastic Investigation
title_fullStr Monitoring the Changes of Material Properties at Bone-Implant Interface during the Healing Process In Vivo: A Viscoelastic Investigation
title_full_unstemmed Monitoring the Changes of Material Properties at Bone-Implant Interface during the Healing Process In Vivo: A Viscoelastic Investigation
title_short Monitoring the Changes of Material Properties at Bone-Implant Interface during the Healing Process In Vivo: A Viscoelastic Investigation
title_sort monitoring the changes of material properties at bone-implant interface during the healing process in vivo: a viscoelastic investigation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360965/
https://www.ncbi.nlm.nih.gov/pubmed/28373978
http://dx.doi.org/10.1155/2017/1945607
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