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Aspirin induces cell death by directly modulating mitochondrial voltage-dependent anion channel (VDAC)

Aspirin induces apoptotic cell death in various cancer cell lines. Here we showed that silencing of VDAC1 protected HeLa cells from aspirin-induced cell death. Compared to the wild type cells, VDAC1 knocked down cells showed lesser change of mitochondrial membrane potential (Δψ(m)), upon aspirin tre...

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Detalles Bibliográficos
Autores principales:	Tewari, Debanjan, Majumdar, Dhriti, Vallabhaneni, Sirisha, Bera, Amal Kanti
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361111/ https://www.ncbi.nlm.nih.gov/pubmed/28327594 http://dx.doi.org/10.1038/srep45184

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