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Glucocorticoid suppression of osteocyte perilacunar remodeling is associated with subchondral bone degeneration in osteonecrosis
Through a process called perilacunar remodeling, bone-embedded osteocytes dynamically resorb and replace the surrounding perilacunar bone matrix to maintain mineral homeostasis. The vital canalicular networks required for osteocyte nourishment and communication, as well as the exquisitely organized...
Autores principales: | Fowler, Tristan W., Acevedo, Claire, Mazur, Courtney M., Hall-Glenn, Faith, Fields, Aaron J., Bale, Hrishikesh A., Ritchie, Robert O., Lotz, Jeffrey C., Vail, Thomas P., Alliston, Tamara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361115/ https://www.ncbi.nlm.nih.gov/pubmed/28327602 http://dx.doi.org/10.1038/srep44618 |
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