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The Immunosuppressant Mycophenolic Acid Alters Nucleotide and Lipid Metabolism in an Intestinal Cell Model

The study objective was to elucidate the molecular mechanisms underlying the negative effects of mycophenolic acid (MPA) on human intestinal cells. Effects of MPA exposure and guanosine supplementation on nucleotide concentrations in LS180 cells were assessed using liquid chromatography-mass spectro...

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Detalles Bibliográficos
Autores principales: Heischmann, Svenja, Dzieciatkowska, Monika, Hansen, Kirk, Leibfritz, Dieter, Christians, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361167/
https://www.ncbi.nlm.nih.gov/pubmed/28327659
http://dx.doi.org/10.1038/srep45088

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