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The Immunosuppressant Mycophenolic Acid Alters Nucleotide and Lipid Metabolism in an Intestinal Cell Model
The study objective was to elucidate the molecular mechanisms underlying the negative effects of mycophenolic acid (MPA) on human intestinal cells. Effects of MPA exposure and guanosine supplementation on nucleotide concentrations in LS180 cells were assessed using liquid chromatography-mass spectro...
Autores principales: | Heischmann, Svenja, Dzieciatkowska, Monika, Hansen, Kirk, Leibfritz, Dieter, Christians, Uwe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361167/ https://www.ncbi.nlm.nih.gov/pubmed/28327659 http://dx.doi.org/10.1038/srep45088 |
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