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Development of a scoring system using a statistical model to predict cure status in patients with cutaneous leishmaniasis

BACKGROUND: The present study was performed to develop a scoring system for predicting cure status in patients with cutaneous leishmaniasis (CL). MATERIALS AND METHODS: This study included 199 patients with CL from Skin Diseases and Leishmaniasis Research Center (Isfahan, Iran). Data were collected...

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Detalles Bibliográficos
Autores principales: Khoshhali, Mehri, Hosseini, Sayed Mohsen, Nilforoushzadeh, Mohammad Ali, Jaffary, Fariba, Baghbaderani, Azadeh Zolfaghari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361442/
https://www.ncbi.nlm.nih.gov/pubmed/28400823
http://dx.doi.org/10.4103/1735-1995.199095
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author Khoshhali, Mehri
Hosseini, Sayed Mohsen
Nilforoushzadeh, Mohammad Ali
Jaffary, Fariba
Baghbaderani, Azadeh Zolfaghari
author_facet Khoshhali, Mehri
Hosseini, Sayed Mohsen
Nilforoushzadeh, Mohammad Ali
Jaffary, Fariba
Baghbaderani, Azadeh Zolfaghari
author_sort Khoshhali, Mehri
collection PubMed
description BACKGROUND: The present study was performed to develop a scoring system for predicting cure status in patients with cutaneous leishmaniasis (CL). MATERIALS AND METHODS: This study included 199 patients with CL from Skin Diseases and Leishmaniasis Research Center (Isfahan, Iran). Data were collected as longitudinal in each visit of patients. We applied ordinal logistic generalized estimating equation regression to predict score on this correlated data. To evaluate the fitted model, split sample validation method was applied. SPSS software was used for data analysis. RESULTS: The regression coefficients of the fitted model were used to calculate score for cure status. Based on split-sample validation method, overall correct classification rate was 82%. CONCLUSION: This study suggested a scoring system predict cure status in CL patients based on clinical characteristics. Using this method, score for a CL patient is easily obtained by physicians or health workers.
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spelling pubmed-53614422017-04-11 Development of a scoring system using a statistical model to predict cure status in patients with cutaneous leishmaniasis Khoshhali, Mehri Hosseini, Sayed Mohsen Nilforoushzadeh, Mohammad Ali Jaffary, Fariba Baghbaderani, Azadeh Zolfaghari J Res Med Sci Original Article BACKGROUND: The present study was performed to develop a scoring system for predicting cure status in patients with cutaneous leishmaniasis (CL). MATERIALS AND METHODS: This study included 199 patients with CL from Skin Diseases and Leishmaniasis Research Center (Isfahan, Iran). Data were collected as longitudinal in each visit of patients. We applied ordinal logistic generalized estimating equation regression to predict score on this correlated data. To evaluate the fitted model, split sample validation method was applied. SPSS software was used for data analysis. RESULTS: The regression coefficients of the fitted model were used to calculate score for cure status. Based on split-sample validation method, overall correct classification rate was 82%. CONCLUSION: This study suggested a scoring system predict cure status in CL patients based on clinical characteristics. Using this method, score for a CL patient is easily obtained by physicians or health workers. Medknow Publications & Media Pvt Ltd 2017-01-27 /pmc/articles/PMC5361442/ /pubmed/28400823 http://dx.doi.org/10.4103/1735-1995.199095 Text en Copyright: © 2017 Journal of Research in Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Khoshhali, Mehri
Hosseini, Sayed Mohsen
Nilforoushzadeh, Mohammad Ali
Jaffary, Fariba
Baghbaderani, Azadeh Zolfaghari
Development of a scoring system using a statistical model to predict cure status in patients with cutaneous leishmaniasis
title Development of a scoring system using a statistical model to predict cure status in patients with cutaneous leishmaniasis
title_full Development of a scoring system using a statistical model to predict cure status in patients with cutaneous leishmaniasis
title_fullStr Development of a scoring system using a statistical model to predict cure status in patients with cutaneous leishmaniasis
title_full_unstemmed Development of a scoring system using a statistical model to predict cure status in patients with cutaneous leishmaniasis
title_short Development of a scoring system using a statistical model to predict cure status in patients with cutaneous leishmaniasis
title_sort development of a scoring system using a statistical model to predict cure status in patients with cutaneous leishmaniasis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361442/
https://www.ncbi.nlm.nih.gov/pubmed/28400823
http://dx.doi.org/10.4103/1735-1995.199095
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