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Large scale genomic analysis shows no evidence for pathogen adaptation between the blood and cerebrospinal fluid niches during bacterial meningitis
Recent studies have provided evidence for rapid pathogen genome diversification, some of which could potentially affect the course of disease. We have previously described such variation seen between isolates infecting the blood and cerebrospinal fluid (CSF) of a single patient during a case of bact...
Autores principales: | Lees, John A., Kremer, Philip H. C., Manso, Ana S., Croucher, Nicholas J., Ferwerda, Bart, Serón, Mercedes Valls, Oggioni, Marco R., Parkhill, Julian, Brouwer, Matthijs C., van der Ende, Arie, van de Beek, Diederik, Bentley, Stephen D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361624/ https://www.ncbi.nlm.nih.gov/pubmed/28348877 http://dx.doi.org/10.1099/mgen.0.000103 |
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