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CDKN2A/p16INK4(a) expression is associated with vascular progeria in chronic kidney disease

Patients with chronic kidney disease (CKD) display a progeric vascular phenotype linked to apoptosis, cellular senescence and osteogenic transformation. This has proven intractable to modelling appropriately in model organisms. We have therefore investigated this directly in man, using for the first...

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Detalles Bibliográficos
Autores principales: Stenvinkel, Peter, Luttropp, Karin, McGuinness, Dagmara, Witasp, Anna, Rashid Qureshi, Abdul, Wernerson, Annika, Nordfors, Louise, Schalling, Martin, Ripsweden, Jonaz, Wennberg, Lars, Söderberg, Magnus, Bárány, Peter, Olauson, Hannes, Shiels, Paul G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361677/
https://www.ncbi.nlm.nih.gov/pubmed/28192277
http://dx.doi.org/10.18632/aging.101173