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Compound effects of aging and experimental FSGS on glomerular epithelial cells

Advanced age portends a poorer prognosis in FSGS. To understand the impact of age on glomerular podocytes and parietal epithelial cells (PECs), experimental FSGS was induced in 3m-old mice (20-year old human age) and 27m-old mice (78-year old human age) by abruptly depleting podocytes with a cytopat...

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Detalles Bibliográficos
Autores principales: Schneider, Remington R.S, Eng, Diana G., Kutz, J. Nathan, Sweetwyne, Mariya T., Pippin, Jeffrey W., Shankland, Stuart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361679/
https://www.ncbi.nlm.nih.gov/pubmed/28222042
http://dx.doi.org/10.18632/aging.101176