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Uniform FDG-PET guided GRAdient Dose prEscription to reduce late Radiation Toxicity (UPGRADE-RT): study protocol for a randomized clinical trial with dose reduction to the elective neck in head and neck squamous cell carcinoma

BACKGROUND: In definitive radiation therapy for head and neck cancer, clinically uninvolved cervical lymph nodes are irradiated with a so-called ‘elective dose’ in order to achieve control of clinically occult metastases. As a consequence of high-resolution diagnostic imaging, occult tumor volume ha...

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Detalles Bibliográficos
Autores principales:	van den Bosch, Sven, Dijkema, Tim, Kunze-Busch, Martina C., Terhaard, Chris H. J., Raaijmakers, Cornelis P. J., Doornaert, Patricia A. H., Hoebers, Frank J. P., Vergeer, Marije R., Kreike, Bas, Wijers, Oda B., Oyen, Wim J. G., Kaanders, Johannes H. A. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361684/ https://www.ncbi.nlm.nih.gov/pubmed/28327089 http://dx.doi.org/10.1186/s12885-017-3195-7

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