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Metastatic BRAF K601E-mutated melanoma reaches complete response to MEK inhibitor trametinib administered for over 36 months

BACKGROUND: The BRAF K601E mutation occurs in 5% of patients with melanoma, and is the third most common type of BRAF mutation. However, treatment with BRAF and mitogen-activated extracellular signal-regulated kinase (MEK) inhibitors is only approved in patients with BRAF V600-positive melanoma, and...

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Detalles Bibliográficos
Autores principales:	Marconcini, Riccardo, Galli, Luca, Antonuzzo, Andrea, Bursi, Simona, Roncella, Claudia, Fontanini, Gabriella, Sensi, Elisa, Falcone, Alfredo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361706/ https://www.ncbi.nlm.nih.gov/pubmed/28344857 http://dx.doi.org/10.1186/s40164-017-0067-4

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