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Leveraging blood serotonin as an endophenotype to identify de novo and rare variants involved in autism

BACKGROUND: Autism spectrum disorder (ASD) is one of the most highly heritable neuropsychiatric disorders, but underlying molecular mechanisms are still unresolved due to extreme locus heterogeneity. Leveraging meaningful endophenotypes or biomarkers may be an effective strategy to reduce heterogene...

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Detalles Bibliográficos
Autores principales:	Chen, Rui, Davis, Lea K., Guter, Stephen, Wei, Qiang, Jacob, Suma, Potter, Melissa H., Cox, Nancy J., Cook, Edwin H., Sutcliffe, James S., Li, Bingshan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361831/ https://www.ncbi.nlm.nih.gov/pubmed/28344757 http://dx.doi.org/10.1186/s13229-017-0130-3

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