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Pterostilbene prevents AKT-ERK axis-mediated polymerization of surface fibronectin on suspended lung cancer cells independently of apoptosis and suppresses metastasis

BACKGROUND: Polymeric fibronectin (polyFN) assembled on suspended breast cancer cells is required for metastasis. Conceivably, drugs that target such polyFN may fight against cancer metastasis. While stilbene analogs trigger pro-apoptotic effect on attached cancer cells, whether they prevent polyFN...

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Detalles Bibliográficos
Autores principales:	Wang, Ying-Jan, Lin, Jing-Fang, Cheng, Li-Hsin, Chang, Wen-Tsan, Kao, Ying-Hsien, Chang, Ming-Min, Wang, Bour-Jr, Cheng, Hung-Chi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361845/ https://www.ncbi.nlm.nih.gov/pubmed/28327179 http://dx.doi.org/10.1186/s13045-017-0441-z

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