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Insights into ClpXP proteolysis: heterooligomerization and partial deactivation enhance chaperone affinity and substrate turnover in Listeria monocytogenes

Caseinolytic proteases (ClpP) are important for recognition and controlled degradation of damaged proteins. While the majority of bacterial organisms utilize only a single ClpP, Listeria monocytogenes expresses two isoforms (LmClpP1 and LmClpP2). LmClpPs assemble into either a LmClpP2 homocomplex or...

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Detalles Bibliográficos
Autores principales:	Balogh, Dóra, Dahmen, Maria, Stahl, Matthias, Poreba, Marcin, Gersch, Malte, Drag, Marcin, Sieber, Stephan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2017
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361862/ https://www.ncbi.nlm.nih.gov/pubmed/28451288 http://dx.doi.org/10.1039/c6sc03438a

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