Cargando…

Insights into ClpXP proteolysis: heterooligomerization and partial deactivation enhance chaperone affinity and substrate turnover in Listeria monocytogenes

Caseinolytic proteases (ClpP) are important for recognition and controlled degradation of damaged proteins. While the majority of bacterial organisms utilize only a single ClpP, Listeria monocytogenes expresses two isoforms (LmClpP1 and LmClpP2). LmClpPs assemble into either a LmClpP2 homocomplex or...

Descripción completa

Detalles Bibliográficos
Autores principales:	Balogh, Dóra, Dahmen, Maria, Stahl, Matthias, Poreba, Marcin, Gersch, Malte, Drag, Marcin, Sieber, Stephan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2017
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361862/ https://www.ncbi.nlm.nih.gov/pubmed/28451288 http://dx.doi.org/10.1039/c6sc03438a

Ejemplares similares

Cryo-EM structure of the ClpXP protein degradation machinery
por: Gatsogiannis, C, et al.
Publicado: (2019)

The Mouse Heart Mitochondria N Terminome Provides Insights into ClpXP-Mediated Proteolysis
por: Hofsetz, Eduard, et al.
Publicado: (2020)

Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex
por: Rizzolo, Kamran, et al.
Publicado: (2021)

A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery
por: Ripstein, Zev A, et al.
Publicado: (2020)

Regulation of Antimycin Biosynthesis Is Controlled by the ClpXP Protease
por: Bilyk, Bohdan, et al.
Publicado: (2020)

Author Correction: Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex
por: Rizzolo, Kamran, et al.
Publicado: (2021)

The Bacterial ClpXP-ClpB Family Is Enriched with RNA-Binding Protein Complexes
por: Auburger, Georg, et al.
Publicado: (2022)

Tailored Phenyl Esters Inhibit ClpXP and Attenuate Staphylococcus aureus α‐Hemolysin Secretion
por: Schwarz, Markus, et al.
Publicado: (2022)

The ClpXP protease is dispensable for degradation of unfolded proteins in Staphylococcus aureus
por: Stahlhut, Steen G., et al.
Publicado: (2017)

Degradation of MinD oscillator complexes by Escherichia coli ClpXP
por: LaBreck, Christopher J., et al.
Publicado: (2020)

The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis
por: Seo, Jae Ho, et al.
Publicado: (2016)

Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates
por: Fei, Xue, et al.
Publicado: (2020)

Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate
por: Fei, Xue, et al.
Publicado: (2020)

Intrinsic Dynamics of the ClpXP Proteolytic Machine Using Elastic Network Models
por: González-Paz, Lenin, et al.
Publicado: (2023)

Strain-Dependent Recognition of a Unique Degradation Motif by ClpXP in Streptococcus mutans
por: Jana, Biswanath, et al.
Publicado: (2016)

The Essential Role of ClpXP in Caulobacter crescentus Requires Species Constrained Substrate Specificity
por: Vass, Robert H., et al.
Publicado: (2017)

Insight into the RssB-Mediated Recognition and Delivery of σ(s) to the AAA+ Protease, ClpXP
por: Micevski, Dimce, et al.
Publicado: (2020)

ClpXP and ClpAP proteolytic activity on divisome substrates is differentially regulated following the Caulobacter asymmetric cell division
por: Williams, Brandon, et al.
Publicado: (2014)

The functional ClpXP protease of Chlamydia trachomatis requires distinct clpP genes from separate genetic loci
por: Pan, Stefan, et al.
Publicado: (2019)

Structural basis for inhibition of a response regulator of σ(S) stability by a ClpXP antiadaptor
por: Dorich, Victoria, et al.
Publicado: (2019)

Small molecule inhibitors of the mitochondrial ClpXP protease possess cytostatic potential and re-sensitize chemo-resistant cancers
por: Meßner, Martina, et al.
Publicado: (2021)

A Functional ClpXP Protease is Required for Induction of the Accessory Toxin Genes, tst, sed, and sec
por: Schelin, Jenny, et al.
Publicado: (2020)

A closed translocation channel in the substrate-free AAA+ ClpXP protease diminishes rogue degradation
por: Ghanbarpour, Alireza, et al.
Publicado: (2023)

NOA1, a Novel ClpXP Substrate, Takes an Unexpected Nuclear Detour Prior to Mitochondrial Import
por: Al-Furoukh, Natalie, et al.
Publicado: (2014)

Optimization of ClpXP activity and protein synthesis in an E. coli extract-based cell-free expression system
por: Shi, Xinying, et al.
Publicado: (2018)

Drosophila protease ClpXP specifically degrades DmLRPPRC1 controlling mitochondrial mRNA and translation
por: Matsushima, Yuichi, et al.
Publicado: (2017)

A Uniform Benchmark for Testing SsrA-Derived Degrons in the Escherichia coli ClpXP Degradation Pathway
por: Klimecka, Maria Magdalena, et al.
Publicado: (2021)

Loss of the ClpXP Protease Leads to Decreased Resistance to Cell-Envelope Targeting Antimicrobials in Bacillus anthracis Sterne
por: Zou, Lang, et al.
Publicado: (2021)

Degradation of the E. coli antitoxin MqsA by the proteolytic complex ClpXP is regulated by zinc occupancy and oxidation
por: Vos, Margaret R., et al.
Publicado: (2021)

Anti-adaptors use distinct modes of binding to inhibit the RssB-dependent turnover of RpoS (σ(S)) by ClpXP
por: Micevski, Dimce, et al.
Publicado: (2015)

The AAA+ protease ClpXP can easily degrade a 3(1) and a 5(2)-knotted protein
por: Sivertsson, Elin M., et al.
Publicado: (2019)

A split protease-E. coli ClpXP system quantifies protein–protein interactions in Escherichia coli cells
por: Wang, Shengchen, et al.
Publicado: (2021)

Listeria monocytogenes utilizes the ClpP1/2 proteolytic machinery for fine-tuned substrate degradation at elevated temperatures
por: Balogh, Dóra, et al.
Publicado: (2022)

ClpXP protease targets long-lived DNA translocation states of a helicase-like motor to cause restriction alleviation
por: Simons, Michelle, et al.
Publicado: (2014)

The SspB adaptor drives structural changes in the AAA+ ClpXP protease during ssrA-tagged substrate delivery
por: Ghanbarpour, Alireza, et al.
Publicado: (2023)

Location of Dual Sites in E. coli FtsZ Important for Degradation by ClpXP; One at the C-Terminus and One in the Disordered Linker
por: Camberg, Jodi L., et al.
Publicado: (2014)

Inducible Synthetic Growth Regulation Using the ClpXP Proteasome Enhances cis,cis-Muconic Acid and Glycolic Acid Yields in Saccharomyces cerevisiae
por: Kakko, Natalia, et al.
Publicado: (2023)

Antibiotic Acyldepsipeptides Stimulate the Streptomyces Clp-ATPase/ClpP Complex for Accelerated Proteolysis
por: Reinhardt, Laura, et al.
Publicado: (2022)

Time-Resolved Proteome Analysis of Listeria monocytogenes during Infection Reveals the Role of the AAA+ Chaperone ClpC for Host Cell Adaptation
por: Birk, Marlène S., et al.
Publicado: (2021)

Targeting altered Nme heterooligomerization in disease?
por: Abu-Taha, Issam H., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_f4s9lqthup3sjv4sqh54kq4hrf