Metal-free O–H/C–H difunctionalization of phenols by o-hydroxyarylsulfonium salts in water

An environmentally benign method for C–H/O–H difunctionalization of phenols with sulfoxides under mild conditions has been developed. The reaction process is mediated by an electrophilic aromatic substitution and subsequent selective aryl or alkyl migration, involving C–S and C–O bond formations wit...

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Detalles Bibliográficos
Autores principales: Chen, Dengfeng, Feng, Qingyuan, Yang, Yunqin, Cai, Xu-Min, Wang, Fei, Huang, Shenlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361865/
https://www.ncbi.nlm.nih.gov/pubmed/28451289
http://dx.doi.org/10.1039/c6sc04504a
Descripción
Sumario:An environmentally benign method for C–H/O–H difunctionalization of phenols with sulfoxides under mild conditions has been developed. The reaction process is mediated by an electrophilic aromatic substitution and subsequent selective aryl or alkyl migration, involving C–S and C–O bond formations with broad substrate scope.

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