Metal-free O–H/C–H difunctionalization of phenols by o-hydroxyarylsulfonium salts in water

An environmentally benign method for C–H/O–H difunctionalization of phenols with sulfoxides under mild conditions has been developed. The reaction process is mediated by an electrophilic aromatic substitution and subsequent selective aryl or alkyl migration, involving C–S and C–O bond formations wit...

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Autores principales: Chen, Dengfeng, Feng, Qingyuan, Yang, Yunqin, Cai, Xu-Min, Wang, Fei, Huang, Shenlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361865/
https://www.ncbi.nlm.nih.gov/pubmed/28451289
http://dx.doi.org/10.1039/c6sc04504a
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author Chen, Dengfeng
Feng, Qingyuan
Yang, Yunqin
Cai, Xu-Min
Wang, Fei
Huang, Shenlin
author_facet Chen, Dengfeng
Feng, Qingyuan
Yang, Yunqin
Cai, Xu-Min
Wang, Fei
Huang, Shenlin
author_sort Chen, Dengfeng
collection PubMed
description An environmentally benign method for C–H/O–H difunctionalization of phenols with sulfoxides under mild conditions has been developed. The reaction process is mediated by an electrophilic aromatic substitution and subsequent selective aryl or alkyl migration, involving C–S and C–O bond formations with broad substrate scope.
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spelling pubmed-53618652017-04-27 Metal-free O–H/C–H difunctionalization of phenols by o-hydroxyarylsulfonium salts in water Chen, Dengfeng Feng, Qingyuan Yang, Yunqin Cai, Xu-Min Wang, Fei Huang, Shenlin Chem Sci Chemistry An environmentally benign method for C–H/O–H difunctionalization of phenols with sulfoxides under mild conditions has been developed. The reaction process is mediated by an electrophilic aromatic substitution and subsequent selective aryl or alkyl migration, involving C–S and C–O bond formations with broad substrate scope. Royal Society of Chemistry 2017-02-01 2016-11-04 /pmc/articles/PMC5361865/ /pubmed/28451289 http://dx.doi.org/10.1039/c6sc04504a Text en This journal is © The Royal Society of Chemistry 2016 http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Chemistry
Chen, Dengfeng
Feng, Qingyuan
Yang, Yunqin
Cai, Xu-Min
Wang, Fei
Huang, Shenlin
Metal-free O–H/C–H difunctionalization of phenols by o-hydroxyarylsulfonium salts in water
title Metal-free O–H/C–H difunctionalization of phenols by o-hydroxyarylsulfonium salts in water
title_full Metal-free O–H/C–H difunctionalization of phenols by o-hydroxyarylsulfonium salts in water
title_fullStr Metal-free O–H/C–H difunctionalization of phenols by o-hydroxyarylsulfonium salts in water
title_full_unstemmed Metal-free O–H/C–H difunctionalization of phenols by o-hydroxyarylsulfonium salts in water
title_short Metal-free O–H/C–H difunctionalization of phenols by o-hydroxyarylsulfonium salts in water
title_sort metal-free o–h/c–h difunctionalization of phenols by o-hydroxyarylsulfonium salts in water
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361865/
https://www.ncbi.nlm.nih.gov/pubmed/28451289
http://dx.doi.org/10.1039/c6sc04504a
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