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Combinatorial selection for replicable RNA by Qβ replicase while maintaining encoded gene function
Construction of a complex artificial self-replication system is challenging in the field of in vitro synthetic biology. Recently, we developed a translation-coupled RNA replication system, wherein an artificial genomic RNA replicates with the Qβ RNA replicase gene encoded on itself. The challenge is...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362092/ https://www.ncbi.nlm.nih.gov/pubmed/28328998 http://dx.doi.org/10.1371/journal.pone.0174130 |