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Tracking the stochastic fate of cells of the renin lineage after podocyte depletion using multicolor reporters and intravital imaging

Podocyte depletion plays a major role in focal segmental glomerular sclerosis (FSGS). Because cells of the renin lineage (CoRL) serve as adult podocyte and parietal epithelial cell (PEC) progenitor candidates, we generated Ren1cCre/R26R-ConfettiTG/WT and Ren1dCre/R26R-ConfettiTG/WT mice to determine...

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Detalles Bibliográficos
Autores principales: Kaverina, Natalya V., Kadoya, Hiroyuki, Eng, Diana G., Rusiniak, Michael E., Sequeira-Lopez, Maria Luisa S., Gomez, R. Ariel, Pippin, Jeffrey W., Gross, Kenneth W., Peti-Peterdi, Janos, Shankland, Stuart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362207/
https://www.ncbi.nlm.nih.gov/pubmed/28329012
http://dx.doi.org/10.1371/journal.pone.0173891

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