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Treatment monitoring in metastatic colorectal cancer patients by quantification and KRAS genotyping of circulating cell-free DNA

Treatment of metastatic colorectal cancer (CRC) has continuously improved over the last decade. However, disease monitoring remains underdeveloped and mostly dependent on imaging e.g. RECIST 1.1 criteria. The genetic landscape of individual cancers and subsequently occurring treatment-induced evolut...

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Detalles Bibliográficos
Autores principales: Berger, Andreas W., Schwerdel, Daniel, Welz, Hanna, Marienfeld, Ralf, Schmidt, Stefan A., Kleger, Alexander, Ettrich, Thomas J., Seufferlein, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362218/
https://www.ncbi.nlm.nih.gov/pubmed/28328955
http://dx.doi.org/10.1371/journal.pone.0174308