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Treatment monitoring in metastatic colorectal cancer patients by quantification and KRAS genotyping of circulating cell-free DNA
Treatment of metastatic colorectal cancer (CRC) has continuously improved over the last decade. However, disease monitoring remains underdeveloped and mostly dependent on imaging e.g. RECIST 1.1 criteria. The genetic landscape of individual cancers and subsequently occurring treatment-induced evolut...
Autores principales: | Berger, Andreas W., Schwerdel, Daniel, Welz, Hanna, Marienfeld, Ralf, Schmidt, Stefan A., Kleger, Alexander, Ettrich, Thomas J., Seufferlein, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362218/ https://www.ncbi.nlm.nih.gov/pubmed/28328955 http://dx.doi.org/10.1371/journal.pone.0174308 |
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