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AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons
Cyclic AMP (cAMP) and protein kinase A (PKA), classical examples of spatially compartmentalized signaling molecules, are critical axon determinants that regulate neuronal polarity and axon formation, yet little is known about micro-compartmentalization of cAMP and PKA signaling and its role in devel...
Autores principales: | Gorshkov, Kirill, Mehta, Sohum, Ramamurthy, Santosh, Ronnett, Gabriele V., Zhou, Feng-Quan, Zhang, Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362298/ https://www.ncbi.nlm.nih.gov/pubmed/28192412 http://dx.doi.org/10.1038/nchembio.2298 |
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