Melatonin attenuates angiotensin II-induced abdominal aortic aneurysm through the down-regulation of matrix metalloproteinases

Abdominal aortic aneurysm (AAA) affects more than 5% of the population in developed countries and the pharmacotherapies for AAA are limited. Here, we explored whether melatonin regulates the development of AAA. In smooth muscle cells, melatonin treatment decreases angiotensin II-induced matrix metal...

Descripción completa

Detalles Bibliográficos
Autores principales: Kong, Jing, Zhang, Ya, Liu, Shanshan, Li, Hongxuan, Liu, Shangming, Wang, Jingjing, Qin, Xiaoteng, Jiang, Xiuxin, Yang, Jianmin, Zhang, Cheng, Zhang, Wencheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362405/
https://www.ncbi.nlm.nih.gov/pubmed/28179581
http://dx.doi.org/10.18632/oncotarget.15093

Ejemplares similares

Ejemplares similares