The ribosomal protein gene RPL5 is a haploinsufficient tumor suppressor in multiple cancer types

For many years, defects in the ribosome have been associated to cancer. Recently, somatic mutations and deletions affecting ribosomal protein genes were identified in a few leukemias and solid tumor types. However, systematic analysis of all 81 known ribosomal protein genes across cancer types is la...

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Detalles Bibliográficos
Autores principales: Fancello, Laura, Kampen, Kim R., Hofman, Isabel J.F., Verbeeck, Jelle, Keersmaecker, Kim De
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362418/
https://www.ncbi.nlm.nih.gov/pubmed/28147343
http://dx.doi.org/10.18632/oncotarget.14895

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