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AMPK-autophagy inhibition sensitizes icaritin-induced anti-colorectal cancer cell activity

The current research studied the potential effect of autophagy on icaritin-induced anti-colorectal cancer (CRC) cell activity. Treatment of icaritin in both primary and established (HT-29) CRC cells induced feedback activation of autophagy, evidenced by p62 degradation, Beclin-1 and autophagy-relate...

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Detalles Bibliográficos
Autores principales:	Zhou, Chunxian, Gu, Jun, Zhang, Gang, Dong, Da, Yang, Qunying, Chen, Min-Bin, Xu, Dongfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362439/ https://www.ncbi.nlm.nih.gov/pubmed/28103582 http://dx.doi.org/10.18632/oncotarget.14718

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