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A new HDAC inhibitor cinnamoylphenazine shows antitumor activity in association with intensive macropinocytosis

Previous studies have shown that intensive macropinocytosis occurs in cancer cells and neutral red (NR) is noted for its capability to enter into the cell massively through a process mimetic to macropinocytosis. In addition, trans-cinnamic acid (tCA) has been found to be an inhibitor of histone deac...

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Detalles Bibliográficos
Autores principales: Zhu, Bing-yan, Shang, Bo-yang, Du, Yue, Li, Yi, Li, Liang, Xu, Xian-dong, Zhen, Yong-su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362440/
https://www.ncbi.nlm.nih.gov/pubmed/28107195
http://dx.doi.org/10.18632/oncotarget.14714