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Detection of CCNE1/URI (19q12) amplification by in situ hybridisation is common in high grade and type II endometrial cancer

One TCGA subgroup of endometrial cancer (EC) is characterised by extensive genomic DNA copy number alterations. CCNE1 located at 19q12 is frequently amplified in EC and a target for anti-cancer therapy. The relevance of URI, also located at 19q12, is unknown. To evaluate the prevalence of 19q12 (CCN...

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Detalles Bibliográficos
Autores principales:	Noske, Aurelia, Brandt, Simone, Valtcheva, Nadejda, Wagner, Ulrich, Zhong, Qing, Bellini, Elisa, Fink, Daniel, Obermann, Ellen C., Moch, Holger, Wild, Peter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362444/ https://www.ncbi.nlm.nih.gov/pubmed/27582547 http://dx.doi.org/10.18632/oncotarget.11605

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