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Regulation of hepatic pyruvate dehydrogenase phosphorylation in offspring glucose intolerance induced by intrauterine hyperglycemia

AIM: Gestational diabetes mellitus (GDM) has been shown to be associated with a high risk of diabetes in offspring. In mitochondria, the inhibition of pyruvate dehydrogenase (PDH) activity by PDH phosphorylation is involved in the development of diabetes. We aimed to determine the role of PDH phosph...

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Detalles Bibliográficos
Autores principales: Zhang, Yong, Zhang, Ying, Ding, Guo-Lian, Liu, Xin-Mei, Ye, Jianping, Sheng, Jian-Zhong, Fan, Jianxia, Huang, He-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362479/
https://www.ncbi.nlm.nih.gov/pubmed/28148899
http://dx.doi.org/10.18632/oncotarget.14837

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