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Hyperhomocysteinemia results from and promotes hepatocellular carcinoma via CYP450 metabolism by CYP2J2 DNA methylation
Hyperhomocysteinemia (HHcy) can result from liver disease or dysfunction and further alters intracellular lipid metabolism. Cytochrome P450 (CYP) arachidonic acid epoxygenases are expressed in human cancers and promote cancer metastasis. This study explored the interaction of Hcy and CYP450 metaboli...
Autores principales: | Zhang, Donghong, Lou, Jinli, Zhang, Xu, Zhang, Lin, Wang, Fei, Xu, Danfei, Niu, Na, Wang, Yidong, Wu, Yue, Cui, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362492/ https://www.ncbi.nlm.nih.gov/pubmed/28030819 http://dx.doi.org/10.18632/oncotarget.14165 |
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