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Hyperhomocysteinemia results from and promotes hepatocellular carcinoma via CYP450 metabolism by CYP2J2 DNA methylation

Hyperhomocysteinemia (HHcy) can result from liver disease or dysfunction and further alters intracellular lipid metabolism. Cytochrome P450 (CYP) arachidonic acid epoxygenases are expressed in human cancers and promote cancer metastasis. This study explored the interaction of Hcy and CYP450 metaboli...

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Detalles Bibliográficos
Autores principales: Zhang, Donghong, Lou, Jinli, Zhang, Xu, Zhang, Lin, Wang, Fei, Xu, Danfei, Niu, Na, Wang, Yidong, Wu, Yue, Cui, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362492/
https://www.ncbi.nlm.nih.gov/pubmed/28030819
http://dx.doi.org/10.18632/oncotarget.14165

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